“… H1 blocker also suppresses the production by epithelial cells or mast … of various chemical mediators and cytokines, such as leukotrienes, arachidonic acid , interleukin (IL)-6, IL-8 and tumor necrosis factor-a (TNF-a), and inhibits … adhesion molecule 1 (CD54) expression on conjunctival cells and activity ⁄migration of eosinophils.”