supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago
supplement:
Arachidonic Acid
drug:
Halothane
Research Papers that Mention the Interaction
“Sevoflurane (0.26 mM) and halothane (0.98 mM) strongly suppressed TXB2 formation by arachidonic acid-stimulated platelets.”
Sevoflurane Inhibits Human Platelet Aggregation and Thromboxane A sub 2 Formation, Possibly by Suppression of Cyclooxygenase Activity“The major products of phospholipase A2 activity, arachidonic acid and lysophosphatidylcholine, when exogenously added, also greatly increased hemolysis induced by halothane , with arachidonic acid most closely resembling the synergism observed with phospholipase A2.”
“These observations indicate that the inhibitory effect of halothane on the formation of 5-lipoxygenase metabolites in leukocytes is mainly due to the inhibition of arachidonic acid release.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback