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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Gliclazide

Research Papers that Mention the Interaction

Gliclazide inhibited the formation of small aggregates induced by low concentrations of arachidonic acid to a limited extent.
Biochemical pharmacology  •  1995  |  View Paper
Gliclazide also enhanced the transformation of both arachidonic acid and PGH2 to PGI2 in guinea-pig aorta, indicating that one of the main enhancing sites is the step of converting PGH2 to PGI2.
Japanese journal of pharmacology  •  1983  |  View Paper
Gliclazide inhibited the thrombin-induced release of radioactive arachidonic acid from [14C] arachidonate-labeled platelets, and the concentration of 50% inhibition (IC50) was 680 μg/ml.
Thrombosis research  •  1981  |  View Paper