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Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Dipyridamole

Research Papers that Mention the Interaction

Direct addition of dipyridamole to vein segments incubated in vitro resulted in a dose-dependent increase in PGI2 production when the incubation was carried out in the presence of arachidonic acid.
Biomedica biochimica acta  •  1990  |  View Paper
Ex vivo, dipyridamole , aspirin and the combination of these drugs inhibited the platelet aggregation induced by PAF and AA.
Thrombosis research  •  1986  |  View Paper
Dipyridamole also inhibited arachidonic acid-induced platelet TXA2 generation at these concentrations.
Prostaglandins  •  1982  |  View Paper
Dipyridamole also inhibited malonyldialdehyde production in response to both thrombin and arachidonic acid.
Dipyridamole potentiated the stimulation of platelet cyclic AMP accumulation by prostacyclin, and also potentiated the stimulatory effect of both arachidonic acid and dihomo-γ-linoleic acid on cyclic GMP accumulation.
Thrombosis research  •  1979  |  View Paper
Dipyridamole induced a marked increase in the coronary flow and PGI2 formation of the hearts but decreased the enhanced myocardial PGI2 biosynthesis after perfusion with arachidonic acid.
Advances in myocardiology  •  1983  |  View Paper
4 Short infusions of acetylsalicylic acid at low concentrations (2.9 μg/ml), dipyridamole (0.6 μg/ml) and sulphinpyrazone (28.7 μg/ml) selectively inhibited the vasoconstrictor phase of the response to AA.
British journal of pharmacology  •  1982  |  View Paper
Dipyridamole enhanced the proliferation of these cells in culture and dipyridamole overcame the inhibitory effect of arachidonic acid on cell proliferation.
Dipyridamole , vitamin E and butylated hydroxytoluene inhibited lipid peroxidation both in cultures treated with media alone and in cultures treated with arachidonic acid.
Artery  •  1982  |  View Paper
The oxygen incorporation into arachidonic acid indicating cyclooxygenase and lipoxydase activity under the influence of lyophilised ram vesicle microsomes was increased by dipyridamole.
Arzneimittel-Forschung  •  1981  |  View Paper
This could explain partly the detected changes in the pulmonary metabolism of arachidonic acid by dipyridamole.
Prostaglandins and medicine  •  1981  |  View Paper
The percentage of arachidonic acid was significantly reduced by dipyridamole , as well as that of different n-3 PUFA present in phospholipid fraction.
Environmental toxicology and pharmacology  •  2002  |  View Paper
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