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“Compounds expected to modulate PHS-dependent co-oxidation of DES increased ( arachidonic acid ) or inhibited (indomethacin) Z,Z-DIES formation of SEMV cells in culture.”
“The oxidation of DES is inhibited whether it is initiated by arachidonic acid or by hydrogen peroxide, indicating that the benzoflavones inhibit PHS by a mechanism different from that of indomethacin.”