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Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Diazepam

supplement:

Arachidonic Acid

Research Papers that Mention the Interaction

However, 357% higher concentration of diazepam (265 microM) as compared to flurazepam (58 microM), was required to inhibit arachidonic acid induced production of malondialdehyde (MDA) by 50%.
One minute preincubation with flurazepam (3-300 microM) or diazepam (3-300 microM) inhibited platelet aggregation, serotonin secretion and prostaglandin synthesis induced by ADP (1-5 microM), epinephrine (1-5 microM), and arachidonic acid (600-1000 microM).
Thrombosis research  •  1985  |  View Paper
In neurosis diazepam (0.5 mg/kg, intraperitoneally, 40 minutes before the investigation) produced a decrease in the brain cortex of levels of arachidonic , oleic and myristic acids.
Farmakologiia i toksikologiia  •  1991  |  View Paper
The inhibition obtained with diazepam could be potentiated in the presence of PGs or arachidonic acid.
The Journal of pharmacology and experimental therapeutics  •  1974  |  View Paper