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Last Updated: 3 years ago

Possible Interaction: Arachidonic Acid and Dantrolene

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supplement:

Arachidonic Acid

drug:

Dantrolene

Research Papers that Mention the Interaction

“ Dantrolene , which blocks the ryanodine receptor (RyR) channel of the ER, significantly inhibited I/R-evoked release of docosahexaenoic, arachidonic , linoleic and oleic acids.”

Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex

Brain Research • 2002 | View Paper

“Preincubation of rabbit washed platelets with dantrolene (50-300 microM) inhibited the platelet aggregation and adenosine triphosphate release induced by arachidonic acid (100 microM), collagen (10 microg/mL), or thrombin (0.1 U/mL) in a dose-dependent manner.”

Inhibitory mechanisms of dantrolene on platelet aggregation.

Thrombosis research • 1999 | View Paper

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