“Thus … of AA to the culture … is skewing the DCs towards the secretion of more IL-12 and less of IL-10 along with the restoration of eicosanoids levels in … COX-2 mediated pathway thereby enhancing the functionality of these cells to be used as a potent cellular vaccine.”
“We hypothesized that exogenous addition of AA to the culture media during DC generation may result in DCs with improved functionality.”