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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Corticosterone
Research Papers that Mention the Interaction
“Addition of corticosterone to the incubation medium also produced a significant decrease in arachidonic acid biosynthesis.”
Arachidonic acid biosynthesis in non-stimulated and adrenocorticotropin-stimulated sertoli and leydig cells“In agreement with this hypothesis, it is found that a promoting effect is exerted by corticosterone on the metabolism of arachidonic acid , leading in turn to an increase in the production of prostacyclin.”
“Graded doses of arachidonic acid (10(-6)-10(-4)M) increased the production of corticosterone and aldosterone in a dose-dependent manner.”
“Incubation with arachidonic acid resulted in an inhibition of ACTH-stimulated corticosterone production.”
“Inhibitors of arachidonic acid release and metabolism blocked corticosterone production in fasciculata cells stimulated with ACTH.”
“6 Cyclo‐oxygenase inhibitors such as indomethacin, aspirin and corticosterone inhibited or abolished the responses to phentolamine and arachidonic acid but did not inhibit the response to PGF2α.”
“Perfusion with arachidonic acid (10(-5) M) and prostacyclin (10(-9) M) for 5 min reversed the supersensitivity induced by corticosterone.”
“The suppressive action of corticosterone on PGE release was prevented by addition to the medium of arachidonic acid (2 mug/ml).”
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