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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Colforsin
Research Papers that Mention the Interaction
“Prostaglandin E1, prostacyclin, carbacyclin, forskolin or dibutyryl cAMP prevented platelet activation by and desensitization to AA and to U46619 under conditions where the formation of thromboxane B2 was not significantly modified.”
Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization.“ Arachidonic acid was shown by immunoblotting to prevent induction of cyclooxygenase-2 by PGE(2), forskolin or dibutyryl cAMP.”
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.“In addition, the fact that stimulators of the adenylyl cyclase catalytic unit, ATP, GTP gamma S and forskolin , when present during pretreatment, attenuate the inhibitory effect of AA may suggest that the catalytic unit is a target of AA.”
“However, the AIF4(-)-stimulated production of 1,2-diacylglycerols and the release of [3H]arachidonic acid ([3H]AA) were inhibited 50-75% by forskolin and 8-bromocAMP.”
“Also, forskolin decreased bradykinin‐induced arachidonic acid release.”
“ Forskolin (5 µM), an adenyl cyclase activator, alone increased the secretion of ME as well as proENK mRNA levels and, when coincubated with AA , showed an additive effect on the secretion of ME and the levels of proENK mRNA.”
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