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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Colforsin

Research Papers that Mention the Interaction

Prostaglandin E1, prostacyclin, carbacyclin, forskolin or dibutyryl cAMP prevented platelet activation by and desensitization to AA and to U46619 under conditions where the formation of thromboxane B2 was not significantly modified.
European journal of pharmacology  •  1986  |  View Paper
Arachidonic acid was shown by immunoblotting to prevent induction of cyclooxygenase-2 by PGE(2), forskolin or dibutyryl cAMP.
Reproduction  •  2007  |  View Paper
In addition, the fact that stimulators of the adenylyl cyclase catalytic unit, ATP, GTP gamma S and forskolin , when present during pretreatment, attenuate the inhibitory effect of AA may suggest that the catalytic unit is a target of AA.
Archives of biochemistry and biophysics  •  2001  |  View Paper
However, the AIF4(-)-stimulated production of 1,2-diacylglycerols and the release of [3H]arachidonic acid ([3H]AA) were inhibited 50-75% by forskolin and 8-bromocAMP.
Prostaglandins, leukotrienes, and essential fatty acids  •  1998  |  View Paper
Also, forskolin decreased bradykinin‐induced arachidonic acid release.
Journal of cellular biochemistry  •  1996  |  View Paper
Forskolin (5 µM), an adenyl cyclase activator, alone increased the secretion of ME as well as proENK mRNA levels and, when coincubated with AA , showed an additive effect on the secretion of ME and the levels of proENK mRNA.
Journal of neurochemistry  •  1995  |  View Paper