Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Arachidonic Acid and Benoxaprofen

Research Papers that Mention the Interaction

3 AA induced a reduction of histamine elevated perfusion pressure which was inhibited, dose‐dependently, by several non‐steroidal anti‐inflammatory agents including indomethacin, phenylbutazone, aspirin, benoxaprofen , BW755C and phenidone.
British journal of pharmacology  •  1984  |  View Paper
In contrast, inhibitors of both cyclooxygenase and lipoxygenase Benoxaprofen and BW755c) prevented the effect of arachidonic acid in the colonic crypts and reduced its effect on colonic tumours but did not alter its effect on the jejunum.
Prostaglandins, leukotrienes, and medicine  •  1984  |  View Paper
Benoxaprofen is an inhibitor pf the lipoxygenase enzyme which converts arachidonic acid to hydroxy derivatives and the leukotrienes.
European journal of rheumatology and inflammation  •  1982  |  View Paper
Benoxaprofen , a new anti-inflammatory agent, has recently been reported to inhibit the production of hydroxy-acid derivatives of arachidonic acid by rabbit PMN lipoxygenase enzymes (Walker & Dawson 1979), whilst possessing relatively low PG cyclo-oxygenase inhibitory activity (Cashin et al 1977).
The Journal of pharmacy and pharmacology  •  1980  |  View Paper