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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
drug:
Atorvastatin
Research Papers that Mention the Interaction
“Although ATV on its own lacked any effect on COX-2 protein induction expression, it enhanced the release of arachidonic acid , the expression of COX-2 protein, and the production of prostaglandin E2 induced by the fungal wall extract zymosan, and to a lower extent the effect of peptidoglycan.”
Cyclooxygenase-2 Induced by Zymosan in Human Monocyte-Derived Dendritic Cells Shows High Stability, and Its Expression Is Enhanced by Atorvastatin“… atorvastatin , significantly … by arachidonic acid 0.75 and 1.5 mmol/L (39.0% and 33.3%, respectively) and by collagen 0.25 and 0.5 μg/…% and 28.5%, respectively) [p < 0.001]; these inhibitions were significantly different (p < 0.05) from the changes that occurred with atorvastatin.”
Comparison of the Effects of Policosanol and Atorvastatin on Lipid Profile and Platelet Aggregation in Patients with Dyslipidaemia and Type 2 Diabetes Mellitus
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