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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Arachidonic Acid and Aspartic Acid

supplement:

Arachidonic Acid

supplement:

Aspartic Acid

Research Papers that Mention the Interaction

Congmuyanosides C, D and echinocystic acid significantly suppressed the superoxide generation induced by phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA).
Planta medica  •  2006  |  View Paper
D exhibited its inhibitory effect even in presence of exogenous arachidonic acid ( AA ) (16.6 microM) whereas Mf lost its inhibitory effect in presence of AA.
Pretreatment of urethane-anaesthetized rats with D (32 mumol kg-1) but not Mf (7.5 mumol kg-1) for 30 min significantly antagonized AA (4 nmol kg-1)-induced hypotension.
General pharmacology  •  1991  |  View Paper
However, the release of … B. Cytochalasins B and D (0.5-1 microM) markedly reduce, … platelets, the metabolism of the liberated arachidonic acid by cyclooxygenase activity to thromboxane B2 and 12-hydroxy-5,8,10-heptadecatrienoic … acid by lipoxygenase activity to 12-hydroxy-5,8,10,14-icosatetraenoic acid.
Proceedings of the National Academy of Sciences of the United States of America  •  1982  |  View Paper