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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Arachidonic Acid
supplement:
Ascorbate
Research Papers that Mention the Interaction
“ Ascorbate induces a 10- to 25-fold rise in platelet guanosine 3'5'-cyclic monophosphate (cGMP) and this action is prevented or reversed by the introduction of aspirin, indomethacin, ro 5,8,11,14-eicosatetraenoic acid (TYA).”
Inhibition by non-steroidal anti-inflammatory agents of the ascorbate-induced elevations of platelet cyclic AMP levels.“Both cell types incorporated 15-3H AA, while Asc supplementation enhanced this 15-3H AA uptake.”
Interrelationship of ascorbate, arachidonic acid and prostaglandin E2 in B16 melanoma cells.“In contrast, the peroxidase cosubstrates propylthiouracil, phenidone, ascorbate and methimazole inhibited arachidonic acid stimulation of conjugate formation but not prostaglandin E2 synthesis.”
“ Arachidonic acid was oxidized by iron ascorbate.”
Previously unknown aldehydic lipid peroxidation compounds of arachidonic acid.“ Ascorbate also potentiated arachidonic acid-induced killing of S. aureus.”
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