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“One of the increasingly recognized adverse events associated with TXA is a dose-dependent increased incidence of seizures.10 Nevertheless, the benefit-to-risk balance between lysine analogs and aprotinin is still the subject of debate.”
“The risk of long-term mortality is also higher after the use of aprotinin in comparison with the use of lysine analogs aminocaproic acid and tranexamic acid.”
Journal of investigational allergology & clinical immunology • 2008 | View Paper
“The risk of long-term mortality is also higher after the use of aprotinin in comparison with the use of lysine analogs aminocaproic acid and tranexamic acid.”