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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Aprotinin
supplement:
Edetic Acid
Research Papers that Mention the Interaction
“For this reason, combination of EDTA and aprotinin for stabilizing BNP in blood samples as used by Pitzalis and colleagues seems to be pointless.”
Methodical approach to collecting and preserving plasma samples containing B‐type natriuretic peptide“The half-life of hTAP-3 in serum was approximately 3.5 min, and the addition of aprotinin and EDTA completely prevented its degradation.”
“The elevated GDA values in serum were suppressed to normal value by the addition of EDTA and aprotinin.”
“The proteolytic conversion of both normal proapo -A-I and proapo -A- ITangier was unaffected by the serine protease inhibitors phenylmethylsulfonyl fluoride (1 mM) or aprotinin (200 Kallikrein-inactivating units/ml), but was inhibited by EDTA (0.1%).”
“A combination of EDTA and aprotinin (0.15 M and 80 Kallikrein Inhibitor Units = KIU/ml) inhibited the tracer degradation, but did not eliminate it completely.”
“While o-phenanthroline, 5-fluorouracil and HgCl2 showed no enzymatic inhibition, EDTA as well as aprotinine inhibited partially in all cases combined.”
“The generation of Cl-s by alcohol and EDTA was inhibited by addition of natural inhibitor of Cl-s but not by soyabean trypsin inhibitor, trasylol and hexadimethrine bromide.”
“These enzymatic activities were inhibited moderately by EDTA and strongly by leupeptin and aprotinin.”
A possible role of chorion protease in shell membrane degradation during development of quail embryos.“Damage to the tracer during the RIA incubation was prevented by the use of 0.25 M EDTA or lower EDTA concentrations plus Trasylol.”
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