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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Aprotinin and Calcium Supplement

Research Papers that Mention the Interaction

Factor VIIa alone or in the presence of calcium , kept its activity even in the presence of high concentrations of aprotinin , inhibition appeared only in the presence of a factor VIIa-tissue factor complex.
Thrombosis research  •  1993  |  View Paper
These suggest that aprotinin is an anti-platelet agent and may exert its action through inhibiting the Ca2+ flux.
Zhongguo yao li xue bao = Acta pharmacologica Sinica  •  1993  |  View Paper
The catalytic activity is not affected by Ca2+ and EDTA but inhibited by aprotinin and a high concentration (10(-6)M) of lima bean trypsin inhibitor.
Biological chemistry Hoppe-Seyler  •  1985  |  View Paper
Calcium ion decreased Km for BAEE, and increased Ki of aprotinin.
Journal of pharmacobio-dynamics  •  1981  |  View Paper