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Last Updated: 2 years ago

Possible Interaction: Apomorphine and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

The stereotypic effect of apomorphine (in mice sensitized by either scopolamine or clonidine) was antagonized by yohimbine and rauwolscine but not by corynanthine.
European journal of pharmacology  •  1985  |  View Paper
The total pecking counts, recorded for 18 min, elicited by a standard dose of apomorphine (1 mg/kg) were inhibited dose-dependently by yohimbine and the neuroleptics.
Neuropharmacology  •  1984  |  View Paper
The effects of clonidine and apomorphine were reversed by yohimbine and haloperidol, respectively.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
The effects of both apomorphine and DP-7-AT were partially inhibited by yohimbine (10 mg/kg i.p.).
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
The alpha-adrenoceptor antagonists prazosin, phenoxybenzamine, and yohimbine also reduced the apomorphine response significantly.
Pharmacology Biochemistry and Behavior  •  2000  |  View Paper
The behavioural effects of the simultaneous injection of yohimbine (500 microg/kg) plus apomorphine (50 microg/kg) and those of the combined treatment of haloperidol (125 microg), a nonspecific dopamine receptor antagonist, with an effective dose of yohimbine (2000 microg/kg) on sexually satiated rats were evaluated.
The combined treatment with subthreshold doses of apomorphine and yohimbine synergised to reverse the sexual inhibition characteristic of sexual exhaustion.
European journal of pharmacology  •  1999  |  View Paper
Apomorphine (5 mg/kg)-induced activity was inhibited by haloperidol and yohimbine but not by prazosin.
Neuropharmacology  •  1987  |  View Paper
The alpha 1-adrenergic antagonists piperoxane (0.03 mg/kg), yohimbine (0.03 mg/kg) or RX781094 (0.07 mg/kg) markedly potentiated apomorphine excitation.
European journal of pharmacology  •  1985  |  View Paper
In the presence of yohimbine (1 microM), apomorphine (10-1000 nM) dose-dependently inhibited the electrically evoked release.
The Journal of pharmacology and experimental therapeutics  •  1985  |  View Paper
The presynaptic inhibitory effects of apomorphine were competitively antagonized by sulpiride, which is considered a specific dopamine receptor antagonist, and by phentolamine and yohimbine which are considered alpha-adrenoceptor antagonists.
European journal of pharmacology  •  1983  |  View Paper
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