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Last Updated: 2 years ago

Possible Interaction: Apomorphine and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Compared to a saline test, APO induced a significant increase of growth hormone (GH), adrenocorticotropin (ACTH), and cortisol (COR) release and a decrease in prolactin (PRL) secretion.
Psychoneuroendocrinology  •  1995  |  View Paper
Apomorphine potentiated the grooming induced by low doses of ACTH.
Pharmacology Biochemistry and Behavior  •  1982  |  View Paper
Compared … adrenocorticotropin … apomorphine (p<0.015 and <0.004, respectively), (2) lower growth hormone response to clonidine (p=0.001), and (3) lower responses to TRH: … thyrotropin (TSH) level (p=0.006) and the difference between 2300 and 0800 h maximum increment in serum TSH values (p=0.0001).
European Neuropsychopharmacology  •  2006  |  View Paper
Single, subcutaneous injection of a subemetic dose of apomorphine (0.75 mg) resulted in a pronounced increase in plasma concentrations of GH, as well as ACTH , beta-endorphin, and cortisol, without induction of any serious adverse drug effects.
Psychoneuroendocrinology  •  1988  |  View Paper
Acute treatment with apomorphine (250 μg · kg−1) resulted in an elevation of plasma ACTH concentration, peak values being reached 15 min after the injection.
Psychopharmacology  •  2004  |  View Paper
Administration of apomorphine prior to immune challenge augmented the normal ACTH response to this stressor at 90 min and there was a corresponding increase in the number of Fos-positive paraventricular nucleus corticotropin-releasing factor cells, paraventricular nucleus oxytocin cells and nucleus tractus solitarius catecholamine cells.
Psychoneuroendocrinology  •  2003  |  View Paper