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Last Updated: 2 years ago

Possible Interaction: Apigenin and Cupric Cation

supplement:

Apigenin

supplement:

Cupric Cation

Research Papers that Mention the Interaction

In summary, coordination of apigenin and genistein to Cu(II ) greatly enhances the antitumoral properties of these flavonoids and potentiates their mechanistic diversity.
Journal of inorganic biochemistry  •  2013  |  View Paper
Addition of Zn2+, Cu2+ and Mn2+ to cell lysates inhibited apigenin's effects on SOD activity.
PloS one  •  2011  |  View Paper
Coordination of Cu(II) increases radical scavenging efficiency of luteolin especially at low pH, while decreases efficiency of apigenin both at low and higher pH as studied by ABTS•+ radical scavenging.
For di-coordinated apigenin the coordination symmetry balances an electron withdrawl effect of Cu(II) resulting in a decrease of phenol acidity and less radical scavenging efficiency compared to parent apigenin.
The journal of physical chemistry. B  •  2019  |  View Paper