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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Apigenin and Colforsin

supplement:

Apigenin

Research Papers that Mention the Interaction

Stimulation of monolayers with forskolin significantly increased their sensitivity to flavonoids: kaempferol (2.5 +/- 0.7 microM) </= apigenin (3.4 +/- 0.9 microM) </= quercetin (4.1 +/- 0.7 microM) </= genistein (6.9 +/- 2.2 microM).
The American journal of physiology  •  1998  |  View Paper
However, apigenin (15-30μM) parallel leftward shifted the concentration-response curves of forskolin and nitroprusside, and significantly increased the pD2 values of these two cyclase activators.
European journal of pharmacology  •  2017  |  View Paper
The total response to forskolin plus apigenin was -2.5 +/- 0.45 mV (n = 6 mice), corresponding to 39% of the response evoked by forskolin only in wild-type mice.
American journal of physiology. Lung cellular and molecular physiology  •  2001  |  View Paper
Stimulation of monolayers with forskolin significantly increased their sensitivity to flavonoids: kaempferol (2.5 ± 0.7 μM) ≤ apigenin (3.4 ± 0.9 μM) ≤ quercetin (4.1 ± 0.7 μM) ≤ genistein (6.9 ± 2.2 μM).
American journal of physiology. Lung cellular and molecular physiology  •  1998  |  View Paper