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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Antipsychotic Agents
supplement:
Vitamin D
Research Papers that Mention the Interaction
“Higher concentrations of 25(OH)D2 were associated with higher risk of suspected and definite psychotic experiences (adjusted odds ratio: OR (95% confidence interval: CI) 1.26 (1.11, 1.43)).”
Serum 25-Hydroxyvitamin D3 and D2 and Non-Clinical Psychotic Experiences in Childhood“Interaction of the antipsychotic drugs with dopamine receptors of the D2, D3 , or D4 subclasses is thought to be important for their mechanisms of action.”
“Also, less patients in the CC group used AP and when they did, they had lower dosages.”
“Additionally, antipsychotic treatments down-regulated INSIGs and up-regulated SREBPs expression in VD deficient rats, and these effects were attenuated when VD status was more sufficient.”
Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: Involvement of the INSIG/SREBP pathway
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