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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antipsychotic Agents
supplement:
Vitamin C
Research Papers that Mention the Interaction
“These results, combined with a growing body of biochemical evidence, suggest that ascorbic acid plays an important role in modulating the behavioral effects of haloperidol and related antipsychotic drugs.”
Ascorbic acid and the behavioral response to haloperidol: implications for the action of antipsychotic drugs.“The data substantiate the hypothesis that ascorbic acid potentiated the activity of typical as well as atypical antipsychotics and that the effect of ascorbic acid on the dopaminergic system is markedly dose dependent; a low dose (100 mg/kg i.p.)”
Antagonistic Activity of Ascorbic Acid (Vitamin C) on Dopaminergic Modulation: Apomorphine-Induced Stereotypic Behavior in Mice“In conclusion, these data provide further in vivo support for the effect of ascorbic acid on dopaminergic system and demonstrate that the antidopaminergic effects of both typical and atypical antipsychotic drugs may be enhanced with concurrent administration of ascorbic acid.”
“The combination of antipsychotic drugs with ascorbic acid 250 mg/kg i.p.”
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