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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antipsychotic Agents
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“We hypothesized that addition of pyridoxine to on-going neuroleptic treatment could improve minor depression in schizophrenic patients.”
[Antidepressive effect of pyridoxine (vitamin B6) in neuroleptic-treated schizophrenic patients with co-morbid minor depression--preliminary open-label trial].“In 110 randomized controlled trials, evidence was found for glycine, sarcosine, N-acetylcysteine, some Chinese and ayurvedic herbs, ginkgo biloba, estradiol, and vitamin B6 to improve psychotic symptoms when added to antipsychotics.”
“Data from some recent studies indicate possible improvements in TD after switching antipsychotics or with the use of amantadine, levetiracetam, piracetam, zonisamide, propranolol, vitamin B6 , or certain unregulated herbal medicines; although significance of these improvements is unclear and require further investigation in randomized controlled trials.”
“Folate, S-adenosylmethionine (SAM) and eicosapentaenoic acid (EPA), for instance, seem to have … properties, zinc may be beneficial in attention deficit hyperactivity disorder (ADHD), vitamin B6 (pyridoxine) could reduce … side effects of antipsychotics and N-acetylcysteine (NAC) seems to be effective … negative symptoms, abnormal movements and akathisia in schizophrenia.”
“One such PLP has an impact on the way neuroleptics are used and monitored.”
Knowledge translation: empowering health professionals to take the lead.
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