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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antipsychotic Agents
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“Thus, the relationship between iron and the neuroleptics may elucidate some new aspects of their mechanism of action.”
Iron modulates neuroleptic-induced effects related to the dopaminergic system.“Alterations in brain iron could play an important role in the development of tardive dyskinesia in patients receiving neuroleptic medication.”
“It also appears that neurolepticdrugs can lead to a redistribution of body iron.'”
“The distribution of iron in the human brain, what is known about its biological functions, and the interaction of neuroleptics with iron suggest that this trace metal may play an important role in the pathogenesis of neuroleptic-induced movement disorders (NIMD).”
“The effect of the neuroleptic drug on iron stores and the involvement of iron in the neuroleptic-induced dopamine supersensitivity suggest that mobilization of iron from the periphery into the brain may play an important role in the mechanism of action of the neuroleptics.”
Prevention of neuroleptic-induced dopamine D2 receptor supersensitivity by chronic iron salt treatment.
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