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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antipsychotic Agents
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Aside from their inhibitory effects on Na currents, most of these antipsychotics showed a higher potency against 5-HT3A receptor-mediated Ca 2 + currents (e.g., IC50 * Ric M. Procyshyn rprocyshyn@bcmhs.bc.ca”
Exercise-induced hippocampal neurogenesis: 5-HT3 receptor antagonism by antipsychotics as a potential limiting factor in Schizophrenia“ Neuroleptic drugs inhibit depolarization-induced Ca uptake in nerve endings, having IC50 values in the micromolar range.”
Calcium channel activity in rat brain synaptosomes: Effects of neuroleptics and other factors regulating phosphorylation and transmitter release“ Neuroleptics , particularly haloperidol and perphenazine, inhibit the activity of brain Ca , Mg-ATPase to a greater extent than the antidepressants benactizin and amphetamine.”
“Psychotropic drugs, especially neuroleptics , reversibly and noncompetitively inhibit the activity of Na, K-ATPase of the brain and Ca , Mg-ATPase of the sarcoplasmatic reticulum.”
“ Ca++ displaced the neuroleptics from the synaptosome membranes.”
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