supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Antipsychotic Agents
supplement:
Ascorbate
Research Papers that Mention the Interaction
“Numerous biochemical and behavioural tests have shown that ascorbate antagonizes the effects of amphetamine and enhances the effects of the antipsychotic drug haloperidol.”
The Role of Ascorbate in Brain: Therapeutic Implications“Acute administration of neuroleptic drugs alters the extracellular level of ascorbate in the neostriatum, and increasing evidence suggests a role for this vitamin in the behavioral, and possibly therapeutic, effects of these drugs.”
Repeated treatment with ascorbate or haloperidol, but not clozapine, elevates extracellular ascorbate in the neostriatum of freely moving rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback