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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antiparkinson Agents
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“In parkinsonian patients, GABA levels were diminished by 36% in the centromedial thalamus, compared to control values.”
A post mortem study on neurochemical markers of dopaminergic, GABA-ergic and glutamatergic neurons in basal ganglia-thalamocortical circuits in Parkinson syndrome“We evaluated the concentrations of the putative transmitter amino acids in the cerebrospinal fluid, and found a significant reduction of glutamate, aspartate, gamma-aminobutyric acid (GABA), and glycine concentrations in parkinsonian patients.”
“Basal levels of Glu and GABA in the GP and SNr were significantly higher in hemiparkinsonian than in intact rats.”
Pallidal Origin of GABA Release within the Substantia Nigra Pars Reticulata during High-Frequency Stimulation of the Subthalamic Nucleus
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