supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Antioxidants
supplement:
Xanthohumol
Research Papers that Mention the Interaction
“We show that xanthohumol strongly inhibited Bcr-Abl expression at both mRNA and protein levels and show that xanthohumol caused elevation of intracellular reactive oxygen species and that the antioxidant N-acetylcysteine blunted xanthohumol-induced events.”
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-κB and p53 modulation“ XN supplementation significantly increased the antioxidant enzyme activities at both 25 and 40 days.”
Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster.“Preservation of retinal CYS and of GSSG and CYSS redox potentials may indicate that XN treatment induces an increased antioxidant response , but further experiments are needed to verify this potential mechanism.”
“Additionally, Xn evidently decreased t-BHP-stimulated cell apoptosis, ROS generation and GSH depletion but increased various anti-oxidative enzymes expression regulated by Keap1-Nrf2/ARE activation, which may be associated with AMPK and GSK3β phosphorylation.”
“In conclusion, our findings suggested that XN enhances antioxidant capacity to improve VC by regulating the Nrf2/Keap1/HO-1 pathway.”
“Xanthohumol XN ), a main prenylated chalcone found in hops, has antioxidant effects to inhibit VC.”
The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback