Possible Interaction: Antioxidants and Vitamin C

“ Vitamin C supplementation may enhance the antioxidant barrier in MS patients.”

“ Antioxidant supplementation significantly increased the levels of vitamin C , β-carotene, α-tocopherol and selenium in plasma.”

“From our limited experience, antioxidant supplementation with vitamin C or E may improve renal transplant function, especially in grafts donated from marginal donors.”

“BACKGROUND We recently reported that antioxidant supplementation with vitamins C and E mitigated ozone related decline in forced expiratory flow (FEF(25-75)) in 158 asthmatic children in an area with high ozone exposure in Mexico City.”

“RESULTS Parenteral administration of vi amin C re sulted in a 100-fold increase (intra-arterial studies) and a 4.5-fold increase (intravenous studies) in ser um antioxidant activity. ”

“We have investigated whether dietary antioxidant supplementation with vitamin C (250 mg/day) can modulate monocyte ICAM-1 expression in healthy male subjects with low plasma vitamin C at baseline.”

“BACKGROUND Epidemiologic studies suggest a protective effect of regular intake of vitamin C and vitamin E as antioxidant in the manifestation of coronary heart disease.”

“Total antioxidant capacity increased significantly following treatment with vitamins C and E (555.4+/-142 vs. 668.6+/-186 micromol/l trolox equivalent; P=0.01) as did vitamin C concentrations (56.5+/-27 vs. 137.7+/-64 micromol/l; P=0.002).”

“Positive correlation between VC and TAS was observed in both in vitro and in healthy volunteers.”

“Serum concentrations of selenium, vitamin C , and vitamin E, the activity of superoxide dismutase and total antioxidant status were significantly (p < 0.05) increased after AO supplementation.”