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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Antioxidants and Urokinase-Type Plasminogen Activator

Research Papers that Mention the Interaction

The combined incubation with reduced glutathione diethyl ester or N-acetylcysteine, antioxidants , suppressed the upregulation of uPA and uPAR mRNA and the increase in plasminogen activator activity by lysoPC.
Arteriosclerosis, thrombosis, and vascular biology  •  2000  |  View Paper
Compared with the untreated hypercholesterolemic group, antioxidant therapy induced significant reductions in renal mRNA levels for procollagen III (to 60% of untreated levels), collagen IV (60%), and TIMP-1 (20%), while uPA levels were significantly increased (to 210%).
Kidney international  •  1998  |  View Paper