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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Antioxidants and Urea

supplement:

Antioxidants

drug:

Urea

Research Papers that Mention the Interaction

Administration of the investigated antioxidants downregulated the marked increase in urea , creatinine, uric acid, CRP, caspase‐3, NO, MDA, VCAM‐1, kidney injury molecule (KIM‐1), STAT‐3, NF‐κB, and DNA fragmentation, and increased Bcl‐2, IL‐10, GSH, and SOD levels induced by CS.
Journal of biochemical and molecular toxicology  •  2019  |  View Paper
Serum levels of creatinine and urea at 24 and 48 h significantly correlated with the Total Antioxidant Activity and lipid peroxidation, respectively.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2017  |  View Paper
In addition, antioxidant treatment partially inhibited the ability of urea to activate transcription of an Egr-1 luciferase reporter gene.
The American journal of physiology  •  1999  |  View Paper
Accordingly, since urea showed a weaker promotion of the related pathways, it caused a depression of the antioxidant system and a consequent increase of ROS.
Journal of proteomics  •  2018  |  View Paper
In addition, antioxidant treatment partially inhibited the ability of urea to activate transcription of an Egr-1 luciferase reporter gene.
American journal of physiology. Renal physiology  •  1999  |  View Paper