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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
supplement:
Trehalose
Research Papers that Mention the Interaction
“In addition, trehalose increased nuclear translocation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) in a p62-dependent manner and enhance expression of its downstream antioxidant factors , heme oxygenase-1 (Ho-1) and nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1 (Nqo1).”
Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways“Simultaneously, Cd-elevated protein levels of hepatic antioxidant enzymes were markedly downregulated by administration with Tr.”
Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis.“Moreover, Cd‐activated Nrf2 target genes, including phase II …)H quinone oxidoreductase 1 and heme oxygenase‐1, direct antioxidant proteins , that is, glutathione peroxidase, superoxide dismutase, catalase, and glutathione biosynthesis‐related proteins, that is, … cysteine ligase modifier subunit, and glutathione reductase, were all downregulated by co‐treatment with Tre.”
“The addition of trehalose and homogenization at 100 MPa increased the total bioaccessibility of antioxidants in FD and AD apples and the total bioaccessibility of flavonoids in the VI samples.”
Antioxidants Bioaccessibility and Lactobacillus salivarius (CECT 4063) Survival Following the In Vitro Digestion of Vacuum Impregnated Apple Slices: Effect of the Drying Technique, the Addition of Trehalose, and High-Pressure Homogenization
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