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Last Updated: 4 years ago

Possible Interaction: Antioxidants and Tadalafil

supplement:

Antioxidants

Research Papers that Mention the Interaction

In conclusion; down-regulation of inflammatory and fibrogenic cytokines expression, restoration of oxidants/antioxidant hemostasis, antioxidant boost and promotion of angiogenesis are implicated in the observed protective effect of tadalafil.
International immunopharmacology  •  2016  |  View Paper
ConclusionsA prolonged exposure to tadalafil decreases antioxidant capacity at resting condition, therefore making subjects more susceptible to the oxidative stress induced by an exhaustive bout of exercise.
European Journal of Applied Physiology  •  2014  |  View Paper
Tadalafil decreased malondialdehyde levels in the I/R group and increased the total antioxidant capacity level.
The Kaohsiung journal of medical sciences  •  2015  |  View Paper
Tadalafil (TAD) prevents the accumulation of ROS and increases antioxidant cellular protective mechanisms.
Acta Neurologica Belgica  •  2013  |  View Paper
Tadalafil also enhanced antioxidant enzyme glutathione S-transferase Kappa-1 (GSKT-1) and downregulated redox regulatory chaperones like heat shock protein 8 (HSPA8), and 75 kD glucose regulatory protein (75GRP).
Basic Research in Cardiology  •  2012  |  View Paper
Cardiac oxidative stress was attenuated and antioxidant capacity was enhanced by tadalafil possibly via up-regulation of mitochondrial superoxide dismutase (MnSOD).
Journal of Pharmacology and Experimental Therapeutics  •  2010  |  View Paper