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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Antioxidants
drug:
Sitagliptin
Research Papers that Mention the Interaction
“Furthermore, sitagliptin treatment significantly attenuated the increase of free-radical formation and the decrease of antioxidant defenses , attenuating therefore the oxidative stress in the kidneys of diabetic animals.”
The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes.“ Sitagliptin alleviated hyperglycemia, hyperlipidemia, HW/BW ratio, histological architecture, oxidative stress, and inflammation, and rejuvenated the antioxidant defenses.”
“ Sitagliptin suppressed Con A-induced oxidative stress and increased antioxidants.”
Anti-fibrotic activity of sitagliptin against concanavalin A-induced hepatic fibrosis. Role of Nrf2 activation/NF-κB inhibition.
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