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“Our data shows for the first time that in young children, administration of sevoflurane , but not propofol, leads to temporally increased antioxidant defense and apoptosis status as well as damage of NSCs.”
“ Sevoflurane preconditioning significantly dose-dependently reduced MDA, IL-1β, IL-6, IL-10 and TNF-α levels and enhanced antioxidant enzyme activities in hippocampus tissue of CIR+SP groups compared to CIR group.”
“ Sevoflurane down‐regulated inflammatory, fibrogenic and angiogenic mediators, and modulated oxidant– antioxidant imbalance, improving lung function in this model of asthma.”