Possible Interaction: Antioxidants and Selenium

“Feeding rats for 30 days with a complex of antioxidant vitamins and selenium produced a sharp enhancement of the antioxidant potential of the liver and a complete suppression of free radical processes in the myocardium.”

“It is concluded that administration of antioxidant vitamins A, E, and C in addition to selenium could accelerate bone healing after long-bone fixative surgery.”

“A great deal of attention has been focused on the possible therapeutic implications of selenium as a potent antioxidant.”

“ Antioxidant supplementation significantly increased the levels of vitamin C, β-carotene, α-tocopherol and selenium in plasma.”

“Serum concentrations of selenium , vitamin C, and vitamin E, the activity of superoxide dismutase and total antioxidant status were significantly (p < 0.05) increased after AO supplementation.”

“Supplementation with selenium provided greater antioxidant protection against oxidative stress generated from experimental infection of lambs with H. contortus.”

“On the basis of results obtained, we conclude that supplementation with selenium provides better antioxidant protection to neutrophils.”

“Incorporation of selenium Se ) atom into small molecules can substantially enhance their antioxidant , anti-inflammatory, antimutagenic, antitumoral or chemopreventive, antiviral, antibacterial, antifungal, antiparasitic and neuroprotective effects.”

“ Selenium can potently stimulate antioxidant defense of cells, especially via upregulation of glutathione (GSH) level and glutathione peroxidase activity.”

“Remarkably, a single dose of Se delivered into the brain drives antioxidant GPX4 expression, protects neurons, and improves behavior in a hemorrhagic stroke model.”