Possible Interaction: Antioxidants and Salvia Miltiorrhiza

“ SM could attenuate markedly lipid peroxide reaction, adjust the imbalance of the three antioxidant enzymes, enhance body's defence capability against damage of active oxygen free radical induced lipid peroxidation.”

“The results suggest that RSMC plays a potential role in antioxidation of lipids or LDL.”

“Furthermore, RSM reduced exhaustive exercise-induced accumulation of the lipid peroxidation byproduct malonaldehyde and elevated antioxidants ' levels, including reduced glutathione and superoxide dismutase, which might be a positive reflection of improved oxidant-antioxidant balance.”

“ Salvia miltiorrhiza have been known to antioxidant property and neuroprotective effects.”

“… EASM enhanced the expression of nuclear factor … factor 2 (Nrf2), which mediated the anti-oxidant response , and its downstream gene heme oxygenase-1 (HO-1) and NAD(P)H quinone dehydrogenase 1 (NQO1) … of expression of kelch-like ECH-associated protein 1 (keap1) both in vitro and in vivo.”

“Correspondingly, DD increased the expression levels of Nrf2 downstream antioxidant genes NQO1, GPX1, HO-1, and GST-π.”

“According to previous studies, many of them contribute to the cardiovascular effects and antioxidant effects of S. miltiorrhiza.”

“These results suggested that antioxidant enzymes and osmolytes are partially involved in the adaptive response to salt stress in Salvia miltiorrhiza , thereby maintaining better plant growth under saline conditions.”