Possible Interaction: Antioxidants and Quercetin

“ Dietary quercetin could increase the antioxidant capacity of blood plasma.”

“Mechanistic studies demonstrated that dietary quercetin significantly attenuated p47phox expression, and inhibited NADPH oxidase-derived oxidative stress in the aortas of HFD-fed ApoE-/- mice, while the expression and activity of antioxidant enzyme heme oxygenase-1 (HO-1) was enhanced after quercetin treatment (P<0.05, all cases).”

“ConclusionsTogether, the results of this study indicated that quercetin increased the antioxidant capacity of the ovary by upregulating the expression of some oxidative stress-related genes both in vivo and in vitro.”

“ Quercetin , melatonin, lithocholic and ursodeoxycholic acids block the effect of those drugs in experimental animals by their antioxidant , anti-apoptotic and/or anti-autophagic properties.”

“ Quercetin prevented the decrease in nuclear …, a key regulator of the antioxidant response , and the increase in reactive oxygen species levels induced by INDO by inhibiting the enhancement of NADPH oxidase … activities as well as the reduction in superoxide dismutase and glutathione peroxidase activities in gastric and ileal tissues.”

“This result indicates that quercetin exhibited, in these cell lines, anti-oxidant more than pro-oxidant ability.”

“It is concluded that rilpivirine causes an anti-adipogenic and pro-inflammatory response pattern but only at high concentrations, whereas quercetin has been observed to decrease inflammation and restore the levels of anti-oxidant enzymes.”

“Out of 16 phenolic compounds tested, several compounds (penta-O-galloyl-β-d-glucose, epicatechin gallate, quercetin, (–)-epicatechin, rutin, quercetin 3-β-d-glucoside, gallic acid, (+)-catechin, ferulic acid, syringic acid) exerted antioxidant activities that were significantly higher compared to Trolox, which was used as a control.”

“ Quercetin , a naturally occurring flavonoid presents in plants and human diet, has been reported to exert antioxidant properties in vivo and in vitro.”

“Our pro‐fibrotic in vitro model, consisting of bleomycin‐triggered BEAS‐2B cells, shows that quercetin boosts the antioxidant response , by increasing Nrf2 activity, and decreases pro‐inflammatory cytokine production in a concentration‐dependent manner.”

“ Quercetin boosts the antioxidant response by increasing Nrf2 activity in vitro.”