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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antioxidants and Oltipraz



Research Papers that Mention the Interaction

Our results show for the first time that OPZ significantly alters the expression of human genes within different functional categories (detoxification of xenobiotics, antioxidant defences , xenobiotic transport, cell cycle and stress responses), at both the mRNA and protein levels, some of which are highly relevant to chemoprevention.
Carcinogenesis  •  2005  |  View Paper
Moreover, OPZ treatment remarkably increased the levels of antioxidant markers such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) in ISO-induced HF rats.
European review for medical and pharmacological sciences  •  2018  |  View Paper
The administration of the dithiolthione antioxidant oltipraz (30 mg/kg/day for 10 days) resulted in a significant decrease (47%) in the incidence of TCDD-induced DNA-SSB.
Toxicology  •  1989  |  View Paper
Both sulforaphane and oltipraz increased the expression of anti-oxidant genes GCLC and NQO1.
Toxicology reports  •  2016  |  View Paper