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Last Updated: 2 months ago

Possible Interaction: Antioxidants and Nitric Oxide

supplement:

Antioxidants

Research Papers that Mention the Interaction

The antioxidant vitamin C increases nitric oxide bioavailability in CHF.
Clinical science  •  2003  |  View Paper
It is possible that the effects of antioxidants may be a consequence of their enhancing or promoting the antiplatelet effects of NO derived from both endothelial cells and platelets.
Antioxidants & redox signaling  •  2012  |  View Paper
The impairment of the release of nitric oxide and vasodilatation may be partially attenuated by antioxidants.
Lipids  •  2007  |  View Paper
The adaptive enhancement of NO synthesis and/or availability activates or increases expression of other protective factors, including heat shock proteins, antioxidants and prostaglandins, making the protection more robust and sustained.
Experimental biology and medicine  •  2006  |  View Paper
Antioxidants , such as melatonin, vitamin C, and vitamin E, probably play important roles in reducing or eliminating the oxidant damage produced by NO.
Annals of the New York Academy of Sciences  •  2005  |  View Paper
Thus, the antioxidant reverses impaired smooth muscle SERCA function in HC, and this is correlated with the improved relaxation to NO.
Circulation research  •  2002  |  View Paper
Selected antioxidants improve intracellular redox state and reverse ECD by improving the bioavailability of NO.
Pathophysiology of Haemostasis and Thrombosis  •  2002  |  View Paper
In addition, L-arginine, the substrate for NO synthesis, and the anti-oxidants ascorbate and α-tocopherol, are able to increase NO synthesis and bioavailability respectively.
Expert opinion on pharmacotherapy  •  2001  |  View Paper
Excess vascular oxidative stress has been associated with impaired NO release, and antioxidant status has been shown to alter endothelium-derived NO bioactivity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2000  |  View Paper
The mechanism of the ascorbic acid effect is unknown, although it has been attributed to an antioxidant function of the vitamin to enhance the synthesis or prevent the breakdown of NO.
Free radical biology & medicine  •  2000  |  View Paper
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