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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Molecular Oxygen
Research Papers that Mention the Interaction
“In the presence of molecular oxygen and iron or copper ions, a number of antioxidants paradoxically generate reactive oxygen species (ROS) leading to free radical damage of nucleic acids and oxidative modification of lipids and proteins.”
gamma-Glutamyltransferase dependent generation of reactive oxygen species from a glutathione/transferrin system.“Both enzymes can reduce molecular oxygen to produce prooxidant species, which, if not countered efficiently by antioxidants , create oxidative stress.”
Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress.“Redox cycling of 6 (and of several putative secondary metabolites) in the presence of intraneuronal antioxidants and molecular oxygen to produce elevated fluxes of cytotoxic reduced oxygen species might contribute to the degeneration of serotonergic pathways.”
“Finally, we combine effects to try to optimize resistance to the addition of molecular oxygen , an important factor in designing carbon‐based antioxidants.”
Stability of carbon‐centered radicals: Effect of functional groups on the energetics of addition of molecular oxygen“ Antioxidants are compounds used to prevent the reactions of organic materials with molecular oxygen.”
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