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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Mito-Q
Research Papers that Mention the Interaction
“In particular, antioxidants conjugated with triphenylphosphonium cation such as mitoquinone , mitovitamin E and mitophenyltertbutyline achieve concentrations in the mitochondrial matrix several-fold greater than those achieved in the cytosol because of the high negative membrane potential of the inner mitochondrial membrane.”
Mitochondrially targeted antioxidants for the treatment of cardiovascular diseases.“In light of these results, studies using mitoquinone as an antioxidant should be interpreted with caution.”
Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis.“Moreover, treatment of MitoQ increased the mRNA levels of downstream antioxidant genes and enhanced the activities of superoxide dismutase, catalase, and glutathione peroxidase.”
Protective effect of MitoQ on oxidative stress-mediated senescence of canine bone marrow mesenchymal stem cells via activation of the Nrf2/ARE pathway.
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