Possible Interaction: Antioxidants and Magnesium

“Taurine and Mg supplementation increased EPC colony formation in healthy men and improved impaired EPC function in SHRs through antioxidation , indicating that the dietary intake of taurine and Mg may prolong lifespan by preventing the progression of cardiovascular diseases.”

“ Magnesium and copper deficiency impair antioxidant defence through decreased synthesis of glutathione and reduced activity of Cu/Zn superoxide dismutase, respectively.”

“ Protective antioxidant enzyme activity is reduced in magnesium and copper deficiency.”

“We found that Mg metal could reduce the cellular oxidative stress damage and elevate the activities of antioxidant enzymes to maintain redox homeostasis.”

“The administration of TRPA1 antagonists, TRPA1 AS, or antioxidant , transiently attenuated MGS , or mechanical and cold allodynia.”

“… magnesium … antioxidant ability by suppressing Nrf2 signalling to decrease antioxidant enzyme mRNA levels and activities (except CuZnSOD mRNA levels and activities); (2) aggravating apoptosis by activating …) by promoting myosin light chain kinase (MLCK) signalling to downregulate TJ gene expression [except claudin-7, ZO-2b and claudin-15 gene expression].”

“These findings demonstrate that magnesium may mediate effective metabolic control by stimulating the antioxidant defense , and increased levels of INSR and GLUT4 in diabetic rats.”

“Calcium and magnesium play an important role in reducing hypertension and antioxidant.”

“This effect is interrelated to the ability of … to scavenges the free radicals, enhances the antioxidant enzymes activity, increases GSH contents, down-regulates … inflammatory responses, ameliorates the iron, calcium, copper, magnesium , manganese levels and inhibiting the gene expression level of … and iNOS in the brain tissues of intoxicated animals.”

“Here we report that the antioxidant agents vitamins A, C, and E act in synergy with magnesium to effectively prevent noise-induced trauma.”