Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Antioxidants and Lutein

supplement:

Antioxidants

supplement:

Lutein

Research Papers that Mention the Interaction

Lutein treatment subsequently blocked the expression of intracellular cell survival proteins, phosphorylated …, phosphorylated extracellular‐regulated kinase 1/2, and nuclear factor‐kB. Suppression of antioxidant defense and … by lutein was further linked to apoptosis induction with elevated caspase‐3 … downregulated expression of Bcl‐2 and poly‐ADP ribose polymerase.
Journal of cellular physiology  •  2020  |  View Paper
The literature indicates that antioxidant supplements plus lutein have a reasonable probability of retarding AMD.
Molecular and Cellular Biochemistry  •  2013  |  View Paper
Abstract Objective: To test the hypothesis that lutein , compared to the placebo, would enhance the total antioxidant status (TAS) in the preterm infants.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians  •  2013  |  View Paper
We tested the hypothesis that lutein would act both by increasing antioxidant capacity and inhibiting OS.
Neonatology  •  2009  |  View Paper
Statistically significant increases in MPOD density were observed in the lutein group for patients with baseline MPOD <or=0.3 optical density units and up to 0.2 optical density units in the lutein plus antioxidant group.
Optometry  •  2007  |  View Paper
Also, LU significantly improved (p < 0.01) the antioxidants [catalase (CAT), superoxide dismutase (SOD)] as well as markedly upregulated (p < 0.01) the protein expression of HO-1 and Nrf2.
Pharmaceutical biology  •  2019  |  View Paper
Pretreatment with lutein significantly increased the total antioxidant capacity with a concomitant decline in the total oxidant status.
These results demonstrated clear evidence that lutein offered a significant protective effect against I/R injury by enhancing antioxidant defense mechanisms.
Molecular medicine reports  •  2015  |  View Paper
Data suggested that xanthophyll supplementation enhanced antioxidant capacity and reduced lipid peroxidation in different tissues of hens and chicks.
British Journal of Nutrition  •  2012  |  View Paper
Other lipid-soluble antioxidants lutein and vitamin E) may also improve the plasma antioxidant capacity.
Clinical nutrition  •  2004  |  View Paper
Serum concentrations of lutein at follow-up, presumably reflecting recent intake of antioxidant supplements , raised MPOD levels significantly at 1.0° and 2.0° (both p < 0.01) but not in the central fovea.
International Journal of Retina and Vitreous  •  2016  |  View Paper