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Last Updated: 2 years ago

Possible Interaction: Antioxidants and Losartan

supplement:

Antioxidants

Research Papers that Mention the Interaction

Topical and oral treatment with losartan significantly increased the antioxidants (glutathione, glutathione peroxidase, superoxide dismutase, and catalase), decreased the lipid peroxidant malondialdehyde, and restored soluble protein, and insoluble protein and various ions (Na+, K+, and Ca2+) in the lens; however, topical treatment had a better effect than oral treatment.
Journal of biochemical and molecular toxicology  •  2019  |  View Paper
Pretreatment with 3 mg/kg losartan decreased the brain IL‐6, MDA and NO metabolites while, increased the anti‐oxidant parameters and improved the performances of rats in the PA, SPT and FST.
Life sciences  •  2018  |  View Paper
These findings suggest that losartan decreases the vascular AGE level, suppresses RAGE and NF-κB activation, and enhances the antioxidant capacity thereby improving the endothelial function, which induce hypertensive vascular remodeling.
Molecular and Cellular Biochemistry  •  2007  |  View Paper