“Inhibitory activity was enhanced by an increase in the number of double bonds, and docosahexaenoic acid (DHA) exerted the highest ….1 mM and 35.5% inhibition even at 10 microM. A hydrophobic radical scavenger (9,10-diphenylanthracene) and two antioxidants (butyrated hydroxytoluene … production of LTB4 , but hydrophilic …) did not.”
“These results suggest that lipophilic anti-oxidative agents , as well as PUFA, inhibit the production of LTB4.”