“Pretreatment with AOX prevented this depressant effect of halothane in the subjects of study 1 (AHR returning to 0.77 ± 0.32 l min−1 %−1, n.s.”
“… antioxidants prevented the reduction … response by halothane , we suggest that this depressant effect may be caused by reactive species produced by a reductive metabolism of halothane during hypoxia … in redox state of carotid body cells by the antioxidants prevented or changed the binding of halothane to its effect site.”