Possible Interaction: Antioxidants and Glutamine

“Interestingly, the antioxidant capacity of ddp-resistant cells was also significantly enhanced and was directly related to the presence of Gln.”

“Conclusions: Glutamine enhances the antioxidant and anti-apoptotic capabilities of melanocytes and protects them against oxidative stress.”

“GLN is a precursor for antioxidants such as glutathione (GSH) and NADPH, and GLN deprivation is therefore predicted to deplete antioxidants and increase reactive oxygen species (ROS).”

“Recent findingsIn addition to its role as a fuel, glutamine regulates gut barrier function, immuno-inflammatory response and antioxidant status.”

“CONCLUSIONS Gl tamine in take in critically ill patients improves the ant ioxidant defenses, w hich leads to lower lipid peroxidation and lower morbidity during admission at the ICU.”

“A few studies suggested that antioxidant supplements might decrease side effects associated with treatment, including vitamin E for hot flashes due to hormonal therapy and glutamine for oral mucositis during chemotherapy.”

“The findings also suggest that glutamine confers metabo-protection with corresponding improvement in adipose and hepatic metabolic function by suppression of ADA/XO activity and enhancement of G6PD-dependent antioxidant defense.”

“Thus, the results indicated that Q was capable of neuroprotection and enhancing the function of antioxidants in fish, which could be predicted to be useful for providing better protection to fish under aquaculture settings with improved Q-rich diets.”

“Supplementation with Q and Q+MQ increased the enzymatic activity of the intestinal microbiota and the antioxidant capacity of blood and revealed a tendency to improve the blood lipid profile.”

“ GLN supplementation increased antioxidant capacity and normalised antioxidant enzyme activities.”

“These results suggest that dietary GLN supplementation decreases oxidative stress-related gene expression, increases the antioxidant potential and may consequently attenuate renal oxidative damage in rats with STZ-induced diabetes.”