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Last Updated: 3 years ago

Possible Interaction: Antioxidants and Glutamic Acid




Glutamic Acid

Research Papers that Mention the Interaction

Glu increases intracellular reactive oxygen species (ROS) production and induces mitochondrial dysfunction as well as decreasing antioxidant defenses such as glutathione (GSH) and glutathione peroxidase activity.
Neuroscience  •  2014  |  View Paper
Antioxidants also prevented the delayed cell death caused by lowering the concentration of cystine in the medium to 5 microM. Incubation of the cells with 10 mM Glu caused a marked decrease in cellular GSH levels.
The antioxidants vitamin E (10-100 microM), idebenone (0.1-3 microM) and vinpocetine (10-100 microM) also provided marked protection against the cytotoxicity of Glu (10 mM) or quisqualate (1 mM).
The Journal of pharmacology and experimental therapeutics  •  1989  |  View Paper
Gly and Glu significantly enhance the activities of superoxide dismutase and glutathione peroxidase, respectively, and increase the total antioxidant capacity of bacteria (P < 0.05).
Food microbiology  •  2022  |  View Paper
Further, enzymatic antioxidants and functional amino acids were significantly up-regulated, with predominant expression of glutamic acid and alanine.
Metabolomics  •  2018  |  View Paper